It has previously been reported that ovine embryos cultured in Synthetic Oviduct Fluid
medium supplemented with 20% human serum (SOF+ HS) develop into lambs with a high
birth weight. We have investigated this phenomenon by culturing ovine zygotes in SOF+ HS
or a serum-free version of Synthetic Oviduct Fluid with BSA and amino acids (SOFaaBSA) in
place of serum. Zygotes were either obtained from superovulated and naturally mated ewes
or produced in vitro. Embryos were subsequently transferred to synchronized recipient ewes …

Lamb birth weight is affected by culture system utilized during in vitro pre-elongation
development of ovine embryos | CiNii Research … Lamb birth weight is affected by culture
system utilized during in vitro pre-elongation development of ovine embryos …