T cells become licensed in the lung to enter the central nervous system

F Odoardi, C Sie, K Streyl, VK Ulaganathan… - Nature, 2012 - nature.com
… CNS after residing transiently within the lung tissues. Inside the lung tissues, they move along
and … We detected that the lung constitutes a niche not only for activated T cells but also for …

Licensed in the Lungs

RM Ransohoff - Nature, 2012 - nature.com
… The cells were initially located in the lung bronchi (air passages) and alveoli (terminal air
sacs), before accumulating in dense immune-cell clusters known as bronchus-associated …

Comparative efficacy and safety of licensed treatments for previously treated non-small cell lung cancer: a systematic review and network meta-analysis

X Armoiry, A Tsertsvadze, M Connock, P Royle… - PLoS …, 2018 - journals.plos.org
… This systematic review with network meta-analysis compared the efficacy and safety of
currently licensed second-line treatments in patients with late stage non-small cell lung cancer (…

Current progress toward a better understanding of drug disposition within the lungs: summary proceedings of the first workshop on drug transporters in the lungs

C Ehrhardt, P Bäckman, W Couet, C Edwards… - Journal of …, 2017 - Elsevier
… the lung? The 3 themes of the workshop were: (1) techniques to study drug transporter
expression and actions in the lungs; … licensed inhaled molecules are substrates are present in the …

Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion

M Galasso, JJ Feld, Y Watanabe, M Pipkin… - Nature …, 2019 - nature.com
… article’s Creative Commons license, unless indicated otherwise in a credit line to the material.
If material is not included in the article’s Creative Commons license and your intended use …

A systematic review of economic evaluations assessing the cost-effectiveness of licensed drugs used for previously treated epidermal growth factor receptor (EGFR) …

D Gallacher, P Auguste, P Royle, H Mistry… - Clinical Drug …, 2019 - Springer
Lung cancer is one of the most commonly diagnosed cancers and the leading cause of … [1],
with non-small lung cancer (NSCLC) accounting for 85%–90% of all forms of lung cancer [2]. …

GM-CSF–licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis

Q Zhou, AWS Ho, A Schlitzer, Y Tang… - The Journal of …, 2014 - journals.aai.org
… lacks lung-resident CD11b + DCs (34), we show that only lung CD11b + DCs are critically
required for Th2 priming and development of allergy. In contrast, lung … that lung epithelial cell-…

Lung transplantation with controlled donation after circulatory death donors

I Inci, S Hillinger, D Schneiter, I Opitz… - Annals of Thoracic and …, 2018 - jstage.jst.go.jp
… We included Maastricht category III DCD lung transplants and all DBD lung transplants
performed between January 2012 and February 2017 at our center. There were 21 transplants …

Long-term outcomes of lung transplant with ex vivo lung perfusion

C Divithotawela, M Cypel, T Martinu, LG Singer… - JAMA …, 2019 - jamanetwork.com
… issued, a patent to CA2944922A1 pending and licensed, a patent to CA2966282A1 issued,
a patent to US10091986B2 issued and licensed, and a patent to WO201818100A1 issued. …

Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs

MG Kris, BE Johnson, LD Berry, DJ Kwiatkowski… - Jama, 2014 - jamanetwork.com
… the care of patients with lung adenocarcinomas. The Lung Cancer Mutation Consortium was
formed to perform multiplexed assays testing adenocarcinomas of the lung for drivers in 10 …