Formation of membrane-less organelles via liquid-liquid phase separation is one way cells
meet the biological requirement for spatiotemporal regulation of cellular components and
reactions. Recently, tau, a protein known for its involvement in Alzheimer's disease and
other tauopathies, was found to undergo liquid–liquid phase separation making it one of
several proteins associated with neurodegenerative diseases to do so. Here, we
demonstrate that tau forms dynamic liquid droplets in vitro at physiological protein levels …