Liver and pancreas:'Castor and Pollux'regarding the relationship between hepatic steatosis and pancreas exocrine insufficiency
Background Pancreatic exocrine insufficiency (PEI) is found in 30–50% of diabetes mellitus
(DM). Insulin resistance is triggering factor in both DM and nonalcoholic fatty liver disease
(NAFLD). Therefore, we aimed to investigate frequency of PEI in NAFLD, and relationship of
fecal pancreatic elastase (PE) levels with liver histology and pancreatic fat. Methods Ninety-
seven biopsy proven NAFLD patients and 50 controls were enrolled. Pancreas exocrine
functions were measured by PE. Magnetic resonance imaging-estimated proton density fat …
(DM). Insulin resistance is triggering factor in both DM and nonalcoholic fatty liver disease
(NAFLD). Therefore, we aimed to investigate frequency of PEI in NAFLD, and relationship of
fecal pancreatic elastase (PE) levels with liver histology and pancreatic fat. Methods Ninety-
seven biopsy proven NAFLD patients and 50 controls were enrolled. Pancreas exocrine
functions were measured by PE. Magnetic resonance imaging-estimated proton density fat …
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