Longitudinal brain and cognitive development of the first 1000 Days: A large multi-cohort multi-scanner study

M Bruchhage, Y Chen, AG Cataldo… - … Society of Magnetic …, 2022 - archive.ismrm.org
The first 1000 days are essential for a child's development, consisting of critical time
windows for brain and cognitive development but also vulnerability. In this large multi-cohort
study, we investigated typical development of 478 children with≤ 6 timepoints across two
different scanners with different acquisition protocols. PACE brain-for-age growth percentiles
and regression slope functions with 95% pointwise confidence intervals identified critical
windows of neurocognitive development. Our results could allow for more appropriate …
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