Lumbar Puncture Complications: A Review of Current Literature

AE Reis, M Spano, C Davis-Hayes… - Current Pain and …, 2024 - Springer
AE Reis, M Spano, C Davis-Hayes, GR Salama
Current Pain and Headache Reports, 2024•Springer
Abstract Purpose of Review This paper reviews the complications of lumbar puncture with a
focus on post-dural puncture headache including pathophysiology, risk factors, prevention,
and treatment. Recent Findings Recent research has focused on understanding the
multifactorial mechanisms of post-dural puncture headache and improving prevention and
treatment strategies. Small caliber, pencil-point type needles are encouraged to minimize
the risk of post-dural puncture headaches, especially in populations that are at higher risk for …
Purpose of Review
This paper reviews the complications of lumbar puncture with a focus on post-dural puncture headache including pathophysiology, risk factors, prevention, and treatment.
Recent Findings
Recent research has focused on understanding the multifactorial mechanisms of post-dural puncture headache and improving prevention and treatment strategies. Small caliber, pencil-point type needles are encouraged to minimize the risk of post-dural puncture headaches, especially in populations that are at higher risk for complication. While new medications and procedures show promise in small cohorts, conservative medical management and epidural blood patch are still the first and second-line treatments for PDPH.
Summary
Post-dural puncture headache is the most frequent complication of lumbar puncture. There are both modifiable and nonmodifiable risk factors to consider when performing this procedure. Conservative medical management and procedure-based therapies exist for when complications of lumbar puncture arise.
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