Lung cancer risk prediction models based on pulmonary nodules: A systematic review
Z Wu, F Wang, W Cao, C Qin, X Dong, Z Yang… - Thoracic …, 2022 - Wiley Online Library
Z Wu, F Wang, W Cao, C Qin, X Dong, Z Yang, Y Zheng, Z Luo, L Zhao, Y Yu, Y Xu, J Li…
Thoracic Cancer, 2022•Wiley Online LibraryBackground Screening with low‐dose computed tomography (LDCT) is an efficient way to
detect lung cancer at an earlier stage, but has a high false‐positive rate. Several pulmonary
nodules risk prediction models were developed to solve the problem. This systematic review
aimed to compare the quality and accuracy of these models. Methods The keywords “lung
cancer,”“lung neoplasms,”“lung tumor,”“risk,”“lung carcinoma”“risk,”“predict,”“assessment,”
and “nodule” were used to identify relevant articles published before February 2021. All …
detect lung cancer at an earlier stage, but has a high false‐positive rate. Several pulmonary
nodules risk prediction models were developed to solve the problem. This systematic review
aimed to compare the quality and accuracy of these models. Methods The keywords “lung
cancer,”“lung neoplasms,”“lung tumor,”“risk,”“lung carcinoma”“risk,”“predict,”“assessment,”
and “nodule” were used to identify relevant articles published before February 2021. All …
Background
Screening with low‐dose computed tomography (LDCT) is an efficient way to detect lung cancer at an earlier stage, but has a high false‐positive rate. Several pulmonary nodules risk prediction models were developed to solve the problem. This systematic review aimed to compare the quality and accuracy of these models.
Methods
The keywords “lung cancer,” “lung neoplasms,” “lung tumor,” “risk,” “lung carcinoma” “risk,” “predict,” “assessment,” and “nodule” were used to identify relevant articles published before February 2021. All studies with multivariate risk models developed and validated on human LDCT data were included. Informal publications or studies with incomplete procedures were excluded. Information was extracted from each publication and assessed.
Results
A total of 41 articles and 43 models were included. External validation was performed for 23.2% (10/43) models. Deep learning algorithms were applied in 62.8% (27/43) models; 60.0% (15/25) deep learning based researches compared their algorithms with traditional methods, and received better discrimination. Models based on Asian and Chinese populations were usually built on single‐center or small sample retrospective studies, and the majority of the Asian models (12/15, 80.0%) were not validated using external datasets.
Conclusion
The existing models showed good discrimination for identifying high‐risk pulmonary nodules, but lacked external validation. Deep learning algorithms are increasingly being used with good performance. More researches are required to improve the quality of deep learning models, particularly for the Asian population.
Wiley Online Library以上显示的是最相近的搜索结果。 查看全部搜索结果