… malonylation as a novel mechanism by which macrophages can control the production of
pro-inflammatory cytokines through GAPDH… identified model in various inflammatory settings is …

… genitalium infection is an important inflammatory signal that … After lipopolysaccharide (LPS)
treatment, macrophages … is a crucial regulatory mechanism modulating the inflammatory …

… -inflammatory macrophages are generated from naive macrophages by pro-inflammatory …
activate the transcription and release of pro-inflammatory mediators. Our study on mice that …

… whether ACC1 promotes GAPDH malonylation-regulated macrophage inflammation, we …
effect of ACC1 deficiency on GAPDH malonylation-induced inflammation. We measured ACC1 …

… Expression of signal transducer and activator of transcription … We have seen evidence
of a diverse set of PTMs in macrophages and … (GAPDH) affects the generation of pro-inflammatory …

… enhanced protein malonylation in macrophage lysates, and … noticeably inhibited the
malonylation of the GAPDH protein. … of how macrophages regulate the expression of inflammation-…

… was successfully and significantly attenuated by overexpression of WT GAPDH but not
C22A GAPDH in RAW264.7 macrophages, which demonstrated the essential role of Cys 22 in …

… Among these, one study identified for the first time that bone marrow-derived macrophages
… malonylation of GAPDH in RA patients may be involved in the inflammatory process of RA. …

… that malonylation plays an important role in inflammation, … The protein contents were
normalized to the level of GAPDH. … Therefore, the weak immunoblot signal in our study may be …

… -inflammatory responses of macrophages. In response to danger signals, activated macrophages
… points for regulating immunometabolism and inflammatory outputs from macrophages. …