Management of cervical preneoplasia starts with an abnormal smear result. The use of the
Bethesda system is recommended. The management of patients with low-grade abnormal
smear results varies around the world. Patients with atypical squamous cells on cytology are
recommended to be subclassified into atypical squamous cells of undetermined significance
(ASCUS) and atypical squamous cells where high-grade squamous intra-epithelial lesions
(HSIL) cannot be excluded (ASCH) groups. While patients with ASCUS can be followed with …

Abstract Treatment of cervical premalignant lesions (cervical intraepithelial neoplasia; CIN)
of different grades is very effective, simple, and safe. The entire transformation zone of the
cervix needs to be treated either by an ablative technique (cryotherapy or thermal ablation)
or an excisional technique (large loop excision of transformation zone or cold knife
conization); the choice of treatment depends on the size and location of the lesion and the
type of the transformation zone. The cure rate after ablative treatment of high-grade CIN may …