Introduction: Since the introduction of tyrosine kinase inhibitors (TKIs) therapy, chronic
myeloid leukemia (CML), has moved from a fatal illness to a manageable disease with a
possible normal lifespan. For this reason is more and more frequent that younger patients
address the possibility to conceive, if men, or get pregnant, if women. Knowledge of safety
and risks concerning both patient and progeny, as well as important cultural, ethical and
psychosocial issues must be taken into consideration. Areas covered: Data published and …