Identification and use of effective cancer chemopreventive agents have become an
important issue in public health-related research. For identification of potential cancer
chemopreventive constituents we have set up a battery of cell-and enzyme-based in vitro
marker systems relevant for prevention of carcinogenesis in vivo. These systems include
modulation of drug metabolism (inhibition of Cyp1A activity, induction of NAD (P) H: quinone
reductase (QR) activity in Hepa1c1c7 murine hepatoma cell culture), determination of …