Importance Oxidative stress and vascular impairment are believed to partly mediate age-
related cognitive decline, a strong risk factor for development of dementia. Epidemiologic
studies suggest that a Mediterranean diet, an antioxidant-rich cardioprotective dietary
pattern, delays cognitive decline, but clinical trial evidence is lacking. Objective To
investigate whether a Mediterranean diet supplemented with antioxidant-rich foods
influences cognitive function compared with a control diet. Design, Setting, and Participants …