OBJECTIVE: The human bone marrow contains mesenchymal stem cells capable of
differentiating along multiple mesenchymal cell lineages. Using a non-human primate
model, we sought to determine whether the systemic infusion of baboon-derived
mesenchymal stem cells was associated with toxicity and whether these cells were capable
of homing to and persisting within the bone marrow. MATERIALS AND METHODS: Five
baboons (Papio anubis) were administered lethal irradiation followed by intravenous …