Mesenchymal stem cells beyond regenerative medicine
R Shammaa, AEH El-Kadiry, J Abusarah… - Frontiers in cell and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are competent suitors of cellular therapy due to their
therapeutic impact on tissue degeneration and immune-based pathologies. Additionally,
their homing and immunomodulatory properties can be exploited in cancer malignancies to
transport pharmacological entities, produce anti-neoplastic agents, or induce anti-tumor
immunity. Herein, we create a portfolio for MSC properties, showcasing their distinct multiple
therapeutic utilities and successes/challenges thereof in both animal studies and clinical …
therapeutic impact on tissue degeneration and immune-based pathologies. Additionally,
their homing and immunomodulatory properties can be exploited in cancer malignancies to
transport pharmacological entities, produce anti-neoplastic agents, or induce anti-tumor
immunity. Herein, we create a portfolio for MSC properties, showcasing their distinct multiple
therapeutic utilities and successes/challenges thereof in both animal studies and clinical …
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