Metal-enhancement study of dual functional photosensitizers with aggregation-induced emission and singlet oxygen generation
Photosensitizers with aggregation-induced emission (AIE-PS) are attractive for image-
guided photodynamic therapy due to their dual functional role in generating singlet oxygen
and producing high fluorescent signal in the aggregated state. However, their brightness
and treatment efficiency maybe limited in current practice. Herein we report the first
systematic investigation on the metal-enhanced fluorescence (MEF) and singlet oxygen
generation (ME-SOG) ability of our newly synthesized AIE-photosensitizers. The Ag@ AIE …
guided photodynamic therapy due to their dual functional role in generating singlet oxygen
and producing high fluorescent signal in the aggregated state. However, their brightness
and treatment efficiency maybe limited in current practice. Herein we report the first
systematic investigation on the metal-enhanced fluorescence (MEF) and singlet oxygen
generation (ME-SOG) ability of our newly synthesized AIE-photosensitizers. The Ag@ AIE …
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