Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images

A Rodriguez, DB Ehlenberger, DL Dickstein, PR Hof… - PloS one, 2008 - journals.plos.org
… a previously computed model of the dendritic tree, comprising a series of nodes of specified
… , three methods for automated dendritic spine analysis from light microscopy images have …

Dendritic spines: Revisiting the physiological role

SB Chidambaram, AG Rathipriya, SR Bolla… - Progress in Neuro …, 2019 - Elsevier
… from neuronal dendrites, primarily localized in the excitatory synapses. Sophisticated
imaging techniques revealed that dendritic spines are complex structures consisting of a dense …

Integration of multiscale dendritic spine structure and function data into systems biology models

JJ Mancuso, J Cheng, Z Yin, JC Gilliam… - Frontiers in …, 2014 - frontiersin.org
… A general pipeline for spine detection is composed of imagemethod to place high resolution
dendritic spine imaging in … characterized dendritic spine imaging with multimodal imaging

Automated algorithms for multiscale morphometry of neuronal dendrites

CM Weaver, PR Hof, SL Wearne, WB Lindquist - Neural computation, 2004 - direct.mit.edu
technique for dendritic spine detection. Rusakov and Stewart construct the medial axis of 2D
images of dendritic … to one consisting of midlines for all dendrite candidates; dendritic radius …

DXplorer: a unified visualization framework for interactive dendritic spine analysis using 3D morphological features

JY Choi, SE Lee, YI Lee, E Cho… - … on Visualization and …, 2021 - ieeexplore.ieee.org
… We demonstrate that the system performs the entire analytic process effectively and provides
… The dataset used in this case study comprised a pair of images taken before and after cLTP …

Computational geometry analysis of dendritic spines by structured illumination microscopy

Y Kashiwagi, T Higashi, K Obashi, Y Sato… - Nature …, 2019 - nature.com
… a method of reliably reconstructing and measuring the surface geometry of dendritic spines
from 3D-SIM images… The final imaging volume spanned a thickness of 5.4 μm, comprising 45 …

Current best practices for analysis of dendritic spine morphology and number in neurodevelopmental disorder research

BZ Li, A Sumera, SA Booker… - ACS Chemical …, 2023 - ACS Publications
… Perspective we highlight several techniques for staining, imaging, and quantifying dendritic
… elements in brain circuits, comprising a dendritic arbor which receives the majority of …

2dSpAn: semiautomated 2-d segmentation, classification and analysis of hippocampal dendritic spine plasticity

S Basu, D Plewczynski, S Saha, M Roszkowska… - …, 2016 - academic.oup.com
Dendritic spine is usually composed of a spine head and … dendritic spines from confocal
microscopy images. However, the 2dSpAn method allows determining the morphology of spines

Automatic reconstruction of dendrite morphology from optical section stacks

S Urban, SM O'Malley, B Walsh… - … to Medical Image …, 2006 - Springer
… A neuron is composed primarily of a cell body (soma) from … received at the dendritic spines
and processed by the dendrites’ specific … the data to be processed and the methods we use to …

Dendritic spine plasticity: function and mechanisms

K Runge, C Cardoso, A De Chevigny - Frontiers in synaptic …, 2020 - frontiersin.org
… of spines, through the repeated imaging of single spines in live animals. Spine dynamics
comprise … of ketamine on spine formation; by this approach, they found that the newly formed …