[HTML][HTML] Methyl linderone suppresses TPA-stimulated IL-8 and MMP-9 expression via the ERK/STAT3 pathway in MCF-7 breast cancer cells
JH Yoon, TH Pham, J Lee, J Lee, HW Ryu… - … of Microbiology and …, 2020 - ncbi.nlm.nih.gov
Methyl linderone (ML), a cyclo-pentenedione, was isolated from the fruit of Lindera
erythrocarpa Makino (family Lauraceae). This plant has well-known anti-inflammatory
effects; however, the anti-cancer effects of ML have not yet been reported. Thus, in the
present study we investigated the effects of ML on the metastasis of human breast cancer
cells. We used 12-O-tetradecanoyl phorbol-13-acetate (TPA)-stimulated MCF-7 cells as the
cell model to study the effects of ML on invasion and migration. ML was found to reduce the …
erythrocarpa Makino (family Lauraceae). This plant has well-known anti-inflammatory
effects; however, the anti-cancer effects of ML have not yet been reported. Thus, in the
present study we investigated the effects of ML on the metastasis of human breast cancer
cells. We used 12-O-tetradecanoyl phorbol-13-acetate (TPA)-stimulated MCF-7 cells as the
cell model to study the effects of ML on invasion and migration. ML was found to reduce the …
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