[HTML][HTML] Methylation-induced repression—belts, braces, and chromatin
AP Bird, AP Wolffe - Cell, 1999 - cell.com
AP Bird, AP Wolffe
Cell, 1999•cell.com). It may also contribute to immobilization of mammalian transposons, suppression of
transcriptional noise, and the control of tissue-specific gene expression, but decisive
evidence on these points is lacking. The theme that is common to all these phenomena is
transcriptional repression. Work on animals, plants, and fungi now leaves little doubt that
gene silencing is a major biological consequence of DNA methylation (
transcriptional noise, and the control of tissue-specific gene expression, but decisive
evidence on these points is lacking. The theme that is common to all these phenomena is
transcriptional repression. Work on animals, plants, and fungi now leaves little doubt that
gene silencing is a major biological consequence of DNA methylation (
). It may also contribute to immobilization of mammalian transposons, suppression of transcriptional noise, and the control of tissue-specific gene expression, but decisive evidence on these points is lacking. The theme that is common to all these phenomena is transcriptional repression. Work on animals, plants, and fungi now leaves little doubt that gene silencing is a major biological consequence of DNA methylation (
cell.com