MicroRNA expression profiling in classic Hodgkin lymphoma
MicroRNAs (miRNAs) are negative regulators of gene expression that play an important role
in hematopoiesis and tumorigenesis. We analyzed miRNA expression in classic Hodgkin
lymphoma (cHL) and the influence of Epstein-Barr virus (EBV) infection on the miRNA
expression profiles. The expression of 157 miRNAs in lymph nodes from 49 cHL patients
and 10 reactive lymph nodes (RLNs) was analyzed by real-time polymerase chain reaction
(PCR). Hierarchic clustering revealed 3 well-defined groups: nodular sclerosis cHL, mixed …
in hematopoiesis and tumorigenesis. We analyzed miRNA expression in classic Hodgkin
lymphoma (cHL) and the influence of Epstein-Barr virus (EBV) infection on the miRNA
expression profiles. The expression of 157 miRNAs in lymph nodes from 49 cHL patients
and 10 reactive lymph nodes (RLNs) was analyzed by real-time polymerase chain reaction
(PCR). Hierarchic clustering revealed 3 well-defined groups: nodular sclerosis cHL, mixed …
MicroRNA expression profiling in classic Hodgkin lymphoma
M Monzo, E Montserrat, R Artells, A López-Guillermo… - Blood, 2007 - upcommons.upc.edu
MicroRNAs (miRNAs) are negative regulators of gene expression that play an important role
in hematopoiesis and tumorigenesis. We analyzed miRNA expression in classic Hodgkin
lymphoma (cHL) and the influence of Epstein-Barr virus (EBV) infection on the miRNA
expression profiles. The expression of 157 miRNAs in lymph nodes from 49 cHL patients
and 10 reactive lymph nodes (RLNs) was analyzed by real-time polymerase chain reaction
(PCR). Hierarchic clustering revealed 3 well-defined groups: nodular sclerosis cHL, mixed …
in hematopoiesis and tumorigenesis. We analyzed miRNA expression in classic Hodgkin
lymphoma (cHL) and the influence of Epstein-Barr virus (EBV) infection on the miRNA
expression profiles. The expression of 157 miRNAs in lymph nodes from 49 cHL patients
and 10 reactive lymph nodes (RLNs) was analyzed by real-time polymerase chain reaction
(PCR). Hierarchic clustering revealed 3 well-defined groups: nodular sclerosis cHL, mixed …
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