Introduction Cancer as one of the most common causes of death has always been one of the
major health challenges globally. Since, the identification of tumors in the early tumor stages
can significantly reduce mortality rates; it is required to introduce novel early detection tumor
markers. MicroRNAs (miRNAs) have pivotal roles in regulation of cell proliferation,
migration, apoptosis, and tumor progression. Moreover, due to the higher stability of miRNAs
than mRNAs in body fluids, they can be considered as non-invasive diagnostic or prognostic …

Cancer is considered as one of the main causes of human deaths globally. Despite the
recent progresses in therapeutic modalities, there is still a high rate of mortality among
cancer patients. Late diagnosis in advanced tumor stages is one of the main reasons for
treatment failure in cancer patients. Therefore, it is required to suggest the novel strategies
for the early tumor detection. MicroRNAs (miRNAs) have critical roles in neoplastic
transformation by regulation of cell proliferation, migration, and apoptosis. They are always …