MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics
A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify
new targets for GBM diagnostics and therapeutics, recent studies have focused on
molecular phenotyping of GBM subtypes. This has resulted in mounting interest in
microRNAs (miRNAs) due to their regulatory capacities in both normal development and in
pathological conditions such as cancer. miRNAs have a wide range of targets, allowing …
remaining incurable with a median survival time of only 15 months. In an effort to identify
new targets for GBM diagnostics and therapeutics, recent studies have focused on
molecular phenotyping of GBM subtypes. This has resulted in mounting interest in
microRNAs (miRNAs) due to their regulatory capacities in both normal development and in
pathological conditions such as cancer. miRNAs have a wide range of targets, allowing …
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