Mild hypoxic ischaemic encephalopathy and long term neurodevelopmental outcome-A systematic review
Aims Hypoxic ischaemic encephalopathy (HIE) remains a significant cause of long term
neurodisability despite therapeutic hypothermia (TH). Infants with mild HIE, representing
50% of those with HIE, are perceived as low risk and are currently not eligible for TH [1]. This
review examines the available evidence of outcome in term infants with mild HIE. Methods
Medline, Embase and Cochrane Clinical Trials databases were searched in March 2017.
Studies with well-defined HIE grading at birth and standardised neurodevelopmental …
neurodisability despite therapeutic hypothermia (TH). Infants with mild HIE, representing
50% of those with HIE, are perceived as low risk and are currently not eligible for TH [1]. This
review examines the available evidence of outcome in term infants with mild HIE. Methods
Medline, Embase and Cochrane Clinical Trials databases were searched in March 2017.
Studies with well-defined HIE grading at birth and standardised neurodevelopmental …
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