Moderate alcohol consumption during pregnancy and the incidence of fetal malformations: a meta-analysis

D Polygenis, S Wharton, C Malmberg… - Neurotoxicology and …, 1998 - Elsevier
To determine whether there is an association between moderate alcohol consumption in the
first trimester of pregnancy and increased risk of fetal malformations, we conducted a
literature search using Medline (1966-present), PsycLit (1974–1995), and EMBASE (1988–
1995). The following inclusion criteria were used to select the studies to be evaluated: 1)
pregnant women; 2) moderate alcohol consumption (> 2 drinks/week to 2 drinks/day); 3)
case-control or cohort studies; 4) presence of an abstainer group (0 to 2 drinks/wk); 5) …
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