Molecular characterization of antigens of lymphatic filarial parasites
ME Selkirk, DA Denham, F Partono, I Sutanto… - Parasitology, 1986 - cambridge.org
Parasitology, 1986•cambridge.org
Three species of filarial worms, Wuchereria bancrofti, Brugia malayi and Brugia timori, are
the causative agents of lymphatic filariasis in man, defined by the characteristic tropism of
adult worms of each species for the afferent lymphatics. Reproductive activity leads to the
release of large numbers of microfilariae, which circulate in the vascular system, and upon
ingestion by an appropriate mosquito vector, develop through to infective third-stage larvae
(L3) within 10–14 days. After a subsequent bloodmeal, the infective larvae enter the …
the causative agents of lymphatic filariasis in man, defined by the characteristic tropism of
adult worms of each species for the afferent lymphatics. Reproductive activity leads to the
release of large numbers of microfilariae, which circulate in the vascular system, and upon
ingestion by an appropriate mosquito vector, develop through to infective third-stage larvae
(L3) within 10–14 days. After a subsequent bloodmeal, the infective larvae enter the …
Three species of filarial worms, Wuchereria bancrofti, Brugia malayi and Brugia timori, are the causative agents of lymphatic filariasis in man, defined by the characteristic tropism of adult worms of each species for the afferent lymphatics. Reproductive activity leads to the release of large numbers of microfilariae, which circulate in the vascular system, and upon ingestion by an appropriate mosquito vector, develop through to infective third-stage larvae (L3) within 10–14 days. After a subsequent bloodmeal, the infective larvae enter the definitive host via the wound and mature to the adult stage over several months, involving two moults, during which the entire nematode exoskeleton (cuticle) is replaced.
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