Mussels fabricate porous glues via multiphase liquid–liquid phase separation of multiprotein condensates
… glue called the byssus plaque. The plaque is an established role model for bioinspired
underwater glues … Distilled concepts suggest that combining phase separation with tunable cross-…
underwater glues … Distilled concepts suggest that combining phase separation with tunable cross-…
Dipeptide-based photoreactive instant glue for environmental and biomedical applications
… The solution was applied to different surfaces and after exposure to a 395 nm wavelength
light, polymerization was initiated and the solution solidified to glue the substrates. …
light, polymerization was initiated and the solution solidified to glue the substrates. …
Cell membrane engineering with synthetic materials: Applications in cell spheroids, cellular glues and microtissue formation
AJR Amaral, G Pasparakis - Acta biomaterialia, 2019 - Elsevier
… For instance, Zhang and co-workers developed an injectable galactosylated hydrogel that
solidifies at physiological temperature to reversibly encapsulate hepatocyte spheroids within …
solidifies at physiological temperature to reversibly encapsulate hepatocyte spheroids within …
Tissue adhesives: From research to clinical translation
… The material should have proper flow characteristics to support easy application to the
target area and also, it should be capable of solidifying rapidly even under mild physiological …
target area and also, it should be capable of solidifying rapidly even under mild physiological …
Hot glue gun releasing biocompatible tissue adhesive
… melt glue gun, melts upon minimal pressure, and is extruded directly onto the wound, where
it solidifies, … Here, we develop a medical glue gun concept in which a cylindrical bioadhesive …
it solidifies, … Here, we develop a medical glue gun concept in which a cylindrical bioadhesive …
Cross-linking by protein oxidation in the rapidly setting gel-based glues of slugs
A Bradshaw, M Salt, A Bell, M Zeitler… - Journal of …, 2011 - journals.biologists.com
… All the other proteins were present in roughly similar amounts in the unset and mature
glue, and at the same relative molecular mass. Finally, as with the mature glue, sodium …
glue, and at the same relative molecular mass. Finally, as with the mature glue, sodium …
Targeting oncogenic K-Ras mutants with a small-molecule degrader through Nedd4-1
T Zeng, T Jiang, B Zhang, T Zhang, W Dai, X Yin, Y Li… - bioRxiv, 2024 - biorxiv.org
… Currently, proteolysis targeting chimeras (PROTACs) and molecular glues are the most
advanced types of small-molecule degraders that can induce a close proximity between an E3 …
advanced types of small-molecule degraders that can induce a close proximity between an E3 …
Targeted protein degradation in drug development: Recent advances and future challenges
J Song, M Hu, J Zhou, S Xie, T Li, Y Li - European Journal of Medicinal …, 2023 - Elsevier
… Additionally, the small molecule BI-3802 acts as a molecular glue to … In recent years, molecular
glue degraders have gradually … on molecular glue inhibitors, and several molecular glue …
glue degraders have gradually … on molecular glue inhibitors, and several molecular glue …
Strong tissue glue with tunable elasticity
R Kelmansky, BJ McAlvin, A Nyska, JC Dohlman… - Acta biomaterialia, 2017 - Elsevier
… proposes a new concept for the formation of super strong and tunable tissue glues. Our bio-…
or other solvents) liquid polymers that solidify after administration while allowing interactions …
or other solvents) liquid polymers that solidify after administration while allowing interactions …
Bone‐adhesive materials: clinical requirements, mechanisms of action, and future perspective
MJ Sánchez‐Fernández, H Hammoudeh… - Advanced Materials …, 2019 - Wiley Online Library
… glues would overcome a major surgical problem. A biodegradable and bone-adhesive glue
… Furthermore, the lower stiffness of bone-adhesive glues would prevent stress shielding as …
… Furthermore, the lower stiffness of bone-adhesive glues would prevent stress shielding as …