… Although not heterobifunctional in the manner of PROTAC molecules, molecular glues promote
… Success against these targets has begun to solidify PROTACs as a therapeutic modality …

… For example, in the silk of silkworms the coat of solidified adhesive (sericin) makes about a …
A thin silk thread attached to the surface by a solidified glue coat will usually detach by a peel-…

… liquid polymer solution, preferably aqueous, that solidifies within seconds or tens of seconds
in vivo… of the catechol to generate cohesive and adhesive strength in the solidified adhesive. …

… hydrated surface salts, as well as delivery of the glue in the form of a complex fluid that does
… mussel secreted a viscous gel that did not solidify and readily dispersed in seawater (movie …

… the bonding site, triggered to polymerize and solidify on demand, and persist underwater as
… responds to ThT, we first exposed untreated glue shavings taken directly from the barnacle …

… glues, which are liquid upon application but solidify after a chemical reaction, or hot-melt (HM)
adhesives, which are tacky in the molten state and harden when they are cooled to room …

… are molecular glues, compounds able to mediate binding interactions between a complex of
proteins which, in the absence of the molecular glue, have … Molecular glue concept solidifies …

… Thalidomide and its analogs are molecular glues (MGs) that lead to targeted ubiquitination
and degradation of key cancer proteins via the cereblon (CRBN) E3 ligase. Here, we develop …

… represent a promising step toward tissue-specific PROTACs and molecular glue degraders.
… topic in the biomedical literature, with new Molecular Glue (MG) degraders and Proteolysis …

… Pharmacological exploitation of this phenomenon via targeted protein degradation (TPD)
can be achieved with molecular glues or bifunctional molecules facilitating the formation of …