A hands-on classroom simulation to demonstrate concepts in enzyme kinetics

M Junker - Journal of Chemical Education, 2010 - ACS Publications
concepts of enzyme kinetics can be developed before introducing more complex reactions
catalyzed by molecular … Competitive inhibitors are bolts with nuts glued onto their ends. They …

Tick attachment cement–reviewing the mysteries of a biological skin plug system

J Suppan, B Engel, M Marchetti‐Deschmann… - Biological …, 2018 - Wiley Online Library
… a component for a reversible tissue glue. Today, no enzyme-based, reversible glue is available
to our knowledge, but this novel concept would facilitate repositioning of tissue fragments …

Adhesion and adhesives–some fundamentals

KW Allen - Studies in Conservation, 1984 - Taylor & Francis
… Thus it will begin with solvent-based adhesives, which solidify by loss of solvent, and this …
solidifying by cooling will be reviewed and finally those which solidify by chemical reaction. …

Wood adhesives and bonding theory

O Ülker - Adhesives–applications and properties, 2016 - books.google.com
… PVA adhesive solidifies by evaporation or by absorption of water by the gluing material.
Solidification time is relatively short, about 45 seconds. The best temperature for using PVA …

[HTML][HTML] Observing classical nucleation theory at work by monitoring phase transitions with molecular precision

M Sleutel, J Lutsko, AES Van Driessche… - Nature …, 2014 - nature.com
… In transient nucleation, as observed in colloid freezing 42 and described in theory 43 ,
liquid-like subcritical clusters are formed first that then gradually solidify into crystalline clusters as …

Repurposing AMP-activated Protein Kinase with Bifunctional Small Molecules to Phosphorylate Non-native Substrates

S Lai - 2022 - search.proquest.com
molecules as mediators of proximity, and examples of natural products such as the plant
hormone auxin act as chemical inducers of proximity (ie, a molecular glue… of the molecular glue

[PDF][PDF] Characterization of Ubiquitin Ligase Targeting by Anticancer Sulfonamides

TCY Ting - 2020 - utswmed-ir.tdl.org
… of the discovered molecular glues are low molecular weight molecules that generally
possess more favorable pharmacokinetic properties. This advantage of molecular glues may be …

In-air microfluidics enables rapid fabrication of emulsions, suspensions, and 3D modular (bio) materials

CW Visser, T Kamperman, LP Karbaat, D Lohse… - Science …, 2018 - science.org
… Finally, the droplets could be solidified by combining two reactive liquids. To demonstrate
this concept, we produced alginate-containing droplets that were solidified via fast (that is, in-…

[HTML][HTML] Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death

SC Chang, P Gopal, S Lim, X Wei… - Cell Chemical …, 2022 - cell.com
Molecular glue concept solidifies. … Indeed, the extensive medicinal chemistry required for
synthesis of such molecules hamper their application as tools to address open questions in the …

Proteolysis-targeting chimeras (PROTACs) as novel biotechnology for cancer therapy

O Fuchs - Biotechnology in Healthcare, 2022 - Elsevier
Molecular glues are a group of small molecules efficient in inducing protein… ligases can
be changed by these molecular glues. The first example of … Molecular glue concept solidifies