Molecular monitoring of residual disease in chronic myelogenous leukemia patients after therapy
R Haas, R Kronenwett, G Sczakiel, A Hochhaus… - … and Molecular Therapy, 1998 - Springer
… reduced considerably if patients are monitored by molecular … , or competitive reverse
transcriptase polymerase chain reaction (… trial of interferon-alpha n 1 for chronic myeloid …
transcriptase polymerase chain reaction (… trial of interferon-alpha n 1 for chronic myeloid …
Chronic myelocytic leukemia–part II: approaches to and molecular monitoring of therapy
TR Randolph - American Society for Clinical Laboratory Science, 2005 - clsjournal.ascls.org
… Competitive or real-time quantitative reverse transcriptase … in CML patients in complete
remission after interferon-alpha … transcriptase-polymerase chain reaction predicts outcome after …
remission after interferon-alpha … transcriptase-polymerase chain reaction predicts outcome after …
Molecular monitoring of chronic myeloid leukemia
T Hughes, S Branford - Seminars in hematology, 2003 - Elsevier
… and lower progression rates than interferon-alpha. However, … (FISH) and qualitative
polymerase chain reaction (PCR) have … The level of BCR-ABL measured by competitive Q-PCR is …
polymerase chain reaction (PCR) have … The level of BCR-ABL measured by competitive Q-PCR is …
Re-emergence of interferon-α in the treatment of chronic myeloid leukemia
M Talpaz, R Hehlmann, A Quintas-Cardama, J Mercer… - Leukemia, 2013 - nature.com
… polymerase chain reaction (PCR) and found that patients who … continuously monitored
BCR-ABL transcript levels by RT–… -positive chronic myelogenous leukemia with interferon-alpha …
BCR-ABL transcript levels by RT–… -positive chronic myelogenous leukemia with interferon-alpha …
Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon α/ara-C
MC Müller, N Gattermann, T Lahaye, MWN Deininger… - Leukemia, 2003 - nature.com
… response of CML patients treated with interferon-alpha monitored by … in chronic myelogenous
leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction. …
leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction. …
Molecular diagnosis and monitoring in the clinical management of patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors
J Ou, JA Vergilio, A Bagg - American journal of hematology, 2008 - Wiley Online Library
… reverse transcriptasepolymerase chain reaction analyses (RT-… pharmacological agents such
as interferon alpha (with or … from the initial use of competitive and limiting dilution RT-PCR …
as interferon alpha (with or … from the initial use of competitive and limiting dilution RT-PCR …
Molecular monitoring of response to imatinib (Glivec®) in CML patients pretreated with interferon alpha. Low levels of residual disease are associated with continuous …
P Paschka, MC Müller, K Merx, S Kreil, C Schoch… - Leukemia, 2003 - nature.com
… of individual patients to treatment or to evaluate the efficacy of a particular … in chronic
myelogenous leukemia patients on interferon-α therapy by competitive polymerase chain reaction. …
myelogenous leukemia patients on interferon-α therapy by competitive polymerase chain reaction. …
Practical monitoring of chronic myelogenous leukemia: when to change treatment
G Saglio, C Fava - Journal of the National Comprehensive Cancer …, 2012 - jnccn.org
… real-time quantitative polymerase chain reaction (RQ-PCR) … , whose efficacy as second-line
therapy in patients with imatinib-… of any products discussed in this article or their competitors. …
therapy in patients with imatinib-… of any products discussed in this article or their competitors. …
A guide to the use of interferon-alpha in the management of chronic myelogenous leukaemia
J Cortes, S O'Brien - BioDrugs, 2000 - Springer
… Patients should be monitored closely with cytogenetic and possibly other analyses such as
fluorescent in situ hybridisation (FISH) and polymerase chain reaction (… Although the efficacy …
fluorescent in situ hybridisation (FISH) and polymerase chain reaction (… Although the efficacy …
Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-α therapy
…, S Pierce, M Talpaz, Leukemia Service* - Annals of Internal …, 1995 - acpjournals.org
… therapy in chronic myelogenous leukemia were initiated by our group in 1982. Since then,
several trials [8-12] have confirmed its efficacy … (ICSG-CML), patients were randomly assigned …
several trials [8-12] have confirmed its efficacy … (ICSG-CML), patients were randomly assigned …