… , prognosis, treatment, and monitoring of CML. The discovery … through reverse transcriptase
polymerase chain reaction (RT-… and has fewer adverse effects than interferon-alpha (IFN-a)[…

… Disease stage is monitored using peripheral blood and … by quantitative real-time
polymerase chain reaction (PCR). … DCC-2036 inhibits ABL in a non-ATP competitive manner; it …

… ), and real time quantitative polymerase chain reaction (RT-Q-… on interferon-alpha therapy
by competitive polymerase chain … to monitor the response of CML patients to interferon-alpha. …

… purity as measured by high performance liquid chromatography. … CML patients or in patients
that do not respond to treatment with … Interferon-alpha preferentially inhibits the outgrowth of …

… by reverse-transcriptase polymerase chain reaction (RT-PCR). A … The goals of CML therapy
and the methods used to monitor … the mutant clone by removing its competitive advantage. …

… polymerase chain reaction (RQ-PCR) tool is used to monitor … Chronic myelogenous leukemia
(CML) is a clonal disorder … disease in patients under interferon-alpha (IFN-α) therapy or …

… treatment outcome in chronic myeloid leukemia (CML). We randomized newly diagnosed
chronic-phase CML patients with a … efficacy and safety the current standard first-line therapy for …

… to monitor the response of CML patients to interferon-alpha. … after interferon-alpha therapy
for chronic myelogenous leukemia: … polymerase chain reaction. Eur J Haematol 2001; 67: 302. …

… quantitative polymerase chain reaction (RQ-PCR) has so far been utilized to monitor minimal
… treated with frontline imatinib without previous exposure to interferon-alpha. ddPCR was …

… Reverse transcriptase-polymerase chain reaction (RT-PCR) … It acts via competitive inhibition
at the ATP-binding site of the … with other available (peg-interferon alpha-2, omacetaxine, …