Motile cilia and airway disease
M Legendre, LE Zaragosi, HM Mitchison - Seminars in cell & …, 2021 - Elsevier
… of airway epithelial development governs the differentiation of motile ciliated cells of the human
respiratory tract… Human cilia dysfunction can arise through genetic mutations and this is a …
respiratory tract… Human cilia dysfunction can arise through genetic mutations and this is a …
[HTML][HTML] Redox regulation of motile cilia in airway disease
ME Price, JH Sisson - Redox Biology, 2019 - Elsevier
… airway ciliary function. We focus on oxidants generated in the airways, cilia redox targets
that modulate ciliary beating and imbalances in redox state that impact health and disease. …
that modulate ciliary beating and imbalances in redox state that impact health and disease. …
Motile ciliary disorders in chronic airway inflammatory diseases: critical target for interventions
W Guan, Y Peng, X Zi, KS Tan, T He, N Zhong… - Current allergy and …, 2018 - Springer
… of motile ciliary disorders and addressed the underlying associations with chronic airway
inflammatory diseases. A … Physicians should be vigilant in screening for motile ciliary disorders, …
inflammatory diseases. A … Physicians should be vigilant in screening for motile ciliary disorders, …
Airway epithelial cell cilia and obstructive lung disease
A Yaghi, MB Dolovich - Cells, 2016 - mdpi.com
… patients with KS had motile cilia with abnormal ciliary structure and uncoordinated beating
… congenital cilia disorders [4,7]. However, when structural cilia defects are not identified, cilia …
… congenital cilia disorders [4,7]. However, when structural cilia defects are not identified, cilia …
Motile ciliopathies
J Wallmeier, KG Nielsen, CE Kuehni… - Nature reviews Disease …, 2020 - nature.com
… motile cilia lining the airways can impair mucociliary clearance and result in chronic destructive
disease of the upper and lower airways… and chronic destructive airway disease is present…
disease of the upper and lower airways… and chronic destructive airway disease is present…
Motile cilia of human airway epithelia are chemosensory
… move mucus out of the lung, and their disruption causes airway disease (11, 12). Because
defense of the airway involves detection of danger signals, we hypothesized that motile cilia …
defense of the airway involves detection of danger signals, we hypothesized that motile cilia …
Respiratory motile cilia dysfunction in a patient with cranioectodermal dysplasia
Y Li, AS Garrod, S Madan‐Khetarpal… - American journal of …, 2015 - Wiley Online Library
… to involve primary cilia defects, we show motile cilia dysfunction in the airway of a patient …
distress, restrictive airway disease with possible obstructive airway involvement, repeated …
distress, restrictive airway disease with possible obstructive airway involvement, repeated …
Motile and non‐motile cilia in human pathology: from function to phenotypes
HM Mitchison, EM Valente - The Journal of pathology, 2017 - Wiley Online Library
… mucus clearance, causing chronic airway diseases which are associated with defects of
laterality, fertility, and brain development. The hallmark disease of motile cilia is PCD 13. About …
laterality, fertility, and brain development. The hallmark disease of motile cilia is PCD 13. About …
Disorders of ciliary motility
MJ Cowan, MT Gladwin, JH Shelhamer - The American journal of the …, 2001 - Elsevier
… anatomy of cilia, beginning with sperm tails in 1959. Camner noted the occurrence of chronic
respiratory tract disease and absence of mucociliary clearance in the airways of 2 men with …
respiratory tract disease and absence of mucociliary clearance in the airways of 2 men with …
Cilia‐related diseases
BA Afzelius - The Journal of Pathology: A Journal of the …, 2004 - Wiley Online Library
… respiratory cilia (9 + 2) is the cause of the airways disease … The hypothesis was put forward
that some embryonal cilia are … without motile cilia (in embryos with the immotile-cilia syndrome…
that some embryonal cilia are … without motile cilia (in embryos with the immotile-cilia syndrome…
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