MsbA transporter-dependent lipid A 1-dephosphorylation on the periplasmic surface of the inner membrane: topography of Francisella novicida LpxE expressed in …
X Wang, MJ Karbarz, SC McGrath, RJ Cotter… - Journal of Biological …, 2004 - ASBMB
The lipid A anchor of Francisella tularensis lipopolysaccharide (LPS) lacks both phosphate
groups present in Escherichia coli lipid A. Membranes of Francisella novicida (an
environmental strain related to F. tularensis) contain enzymes that dephosphorylate lipid A
and its precursors at the 1-and 4′-positions. We now report the cloning and
characterization of a membrane-bound phosphatase of F. novicida that selectively
dephosphorylates the 1-position. By transferring an F. novicida genomic DNA library into E …
groups present in Escherichia coli lipid A. Membranes of Francisella novicida (an
environmental strain related to F. tularensis) contain enzymes that dephosphorylate lipid A
and its precursors at the 1-and 4′-positions. We now report the cloning and
characterization of a membrane-bound phosphatase of F. novicida that selectively
dephosphorylates the 1-position. By transferring an F. novicida genomic DNA library into E …
以上显示的是最相近的搜索结果。 查看全部搜索结果