… analyses we propose that phylogenetically related M. tuberculosis isolated from severe
TB cases develops mechanisms to escape cytosolic recognition and consequently lower …

… surveillance pathway (CSP) and induce innate immune responses, but how the host detects
vacuolar pathogens like Mycobacterium tuberculosis is poorly understood. We show that M. …

… components, to evade host clearance. In this … mycobacterial DNA on mammalian hosts
were receiving attention decades ago, 9 host-responsive DNA-dependent cytosolic surveillance …

… sick with tuberculosis. Mycobacterium tuberculosis (MTB) is an intracellular parasite that mainly
… , contributes to the intracellular persistence of MTB and avoids immune recognition [121]. …

… Mycobacterium tuberculosis (Mtb) uses efficient strategies to evade the eradication by …
The latter approach not only allows monitoring of bacteria-induced phagosomal rupture or …

… tuberculosis, because it is a vast reservoir of potential reactivation and transmission. This
article explains how the pathogen evades … tuberculosis enters into the cytosol of the infected …

… and multifactorial ability of pathogenic mycobacteria to prevent or evade effective host responses.
… tuberculosis to escape from phagosomes into the cytosol of infected macrophages in a …

… Intracellular pathogens like Mycobacterium tuberculosis are known to avoid lysosomal fusion
through the manipulation of host signal transduction pathways [1]. Following phagocytosis …

… Mycobacterium tuberculosis (Mtb). Mtb subverts the macrophage's mechanisms of intracellular
… might allow Mtb to evade immune responses and mediate severe lung infections. In fact, …

… tuberculosis antigens and thus avoids false positive results from prior BCG vaccination 8 . In
… innate immune cell activity but also contributed to the restriction of intracellular survival of M. …