Nanoparticles for targeted drug delivery to cancer stem cells: a review of recent advances
Cancer stem cells (CSCs) are a subpopulation of cells that can initiate, self-renew, and
sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug
resistance in cancer therapy. CSCs reside within a niche maintained by multiple unique
factors in the microenvironment. These factors include hypoxia, excessive levels of
angiogenesis, a change of mitochondrial activity from aerobic aspiration to aerobic
glycolysis, an upregulated expression of CSC biomarkers and stem cell signaling, and an …
sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug
resistance in cancer therapy. CSCs reside within a niche maintained by multiple unique
factors in the microenvironment. These factors include hypoxia, excessive levels of
angiogenesis, a change of mitochondrial activity from aerobic aspiration to aerobic
glycolysis, an upregulated expression of CSC biomarkers and stem cell signaling, and an …
[PDF][PDF] Nanoparticles for targeted drug delivery to cancer stem cells: a review of recent advances. Nanomaterials. 2021; 11: 1755
Cancer stem cells (CSCs) are a subpopulation of cells that can initiate, self-renew, and
sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug
resistance in cancer therapy. CSCs reside within a niche maintained by multiple unique
factors in the microenvironment. These factors include hypoxia, excessive levels of
angiogenesis, a change of mitochondrial activity from aerobic aspiration to aerobic
glycolysis, an upregulated expression of CSC biomarkers and stem cell signaling, and an …
sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug
resistance in cancer therapy. CSCs reside within a niche maintained by multiple unique
factors in the microenvironment. These factors include hypoxia, excessive levels of
angiogenesis, a change of mitochondrial activity from aerobic aspiration to aerobic
glycolysis, an upregulated expression of CSC biomarkers and stem cell signaling, and an …
以上显示的是最相近的搜索结果。 查看全部搜索结果