Neonatal inhalatory anesthetic exposure: reproductive changes in male rats

AC Arena, OCM Pereira - Comparative Biochemistry and Physiology Part C …, 2002 - Elsevier
We investigated the effects of an inhalatory anesthetic (ethyl ether) during the neonatal
period of brain sexual differentiation on the later fertility and sexual behavior of male rats.
Animals were exposed to ethyl ether immediately after birth. At adulthood, body weight,
testes wet weight, and plasma testosterone levels were not affected; however, neonatal
exposure to ether showed alterations on male fertility: a decrease in the number of
spermatids and spermatozoa, an increase in the transit time of cauda epididymal …
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