Neoplastic and nonneoplastic lesions in untreated F344 rats used as controls in
carcinogenesis tests were tabulated and evaluated. The most common neoplasms in 1794
male rats were testicular interstitial cell tumors, leukemias, pituitary adenomas, and adrenal
pheochromocytomas. In 1754 female rats, common tumors were pituitary adenomas,
mammamary fibroadenomas, uterine endometrial stromal polyps, and leukemias. A variety
of less common and rare tumors were seen in almost every tissue. A few malignant …

… The Rat Genome Database (RGD) was established in 1999 and rapidly became the premier
site for genetic, genomic, phenotype, and disease-related data generated from rat research.
In addition, RGD has expanded to include a large body of structured and standardized data
for eight species (rat, mouse, human, chinchilla, bonobo, 13-lined ground squirrel, dog and
pig). Much of this data is the result of manual curation work by RGD curators. In other
instances, it has been imported into RGD from other databases through custom ELT (Extract …