Nerve growth factor, stress and diseases

FM Ceci, G Ferraguti, C Petrella… - Current Medicinal …, 2021 - ingentaconnect.com
FM Ceci, G Ferraguti, C Petrella, A Greco, P Tirassa, A Iannitelli, M Ralli, M Vitali, M Ceccanti
Current Medicinal Chemistry, 2021ingentaconnect.com
… Our organisms respond to stress by activating the adaptive stress system to activate
compensatory responses for restoring homeostasis. Nerve Growth Factor (NGF) was discovered
as a signaling molecule involved in survival, protection, differentiation, and proliferation of
sympathetic and peripheral sensory neurons. NGF mediates … Stress mediators like
neuroendocrine hormones, cytokines, catecholamine, neurotransmitters and growth factors
regulate both basal and challenged homeostasis and could be responsible for …
Stress is a constant threat for homeostasis and is represented by different extrinsic and intrinsic stimuli (stressors, Hans Selye’s
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