Neurite Outgrowth in Brain Neurons Induced by Heparin-binding Growth-associated Molecule (HB-GAM) Depends on the Specific Interaction of HB-GAM with …
T Kinnunen, E Raulo, R Nolo, M Maccarana… - Journal of Biological …, 1996 - ASBMB
Heparin-binding growth-associated molecule (HB-GAM) is a cell surface-and extracellular
matrix-associated protein that lines developing axons in vivo and promotes neurite
outgrowth in vitro. Because N-syndecan (syndecan-3) was found to function as a receptor in
HB-GAM-induced neurite outgrowth, we have now studied whether the heparan sulfate side
chains of N-syndecan play a role in HB-GAM-neuron interactions. N-Syndecan from
postnatal rat brain was found to inhibit HB-GAM-induced but not laminin-induced neurite …
matrix-associated protein that lines developing axons in vivo and promotes neurite
outgrowth in vitro. Because N-syndecan (syndecan-3) was found to function as a receptor in
HB-GAM-induced neurite outgrowth, we have now studied whether the heparan sulfate side
chains of N-syndecan play a role in HB-GAM-neuron interactions. N-Syndecan from
postnatal rat brain was found to inhibit HB-GAM-induced but not laminin-induced neurite …
以上显示的是最相近的搜索结果。 查看全部搜索结果