Neurocognitive functioning predicts suicidal behaviour in young people with affective disorders
Journal of affective disorders, 2021•Elsevier
Background Neurocognitive impairment is recognised as a risk factor for suicidal behaviour
in adults. The current study aims to determine whether neurocognitive deficits also predict
ongoing or emergent suicidal behaviour in young people with affective disorders. Methods
Participants were aged 12-30 years and presented to early intervention youth mental health
clinics between 2008 and 2018. In addition to clinical assessment a standardised
neurocognitive assessment was conducted at baseline. Clinical data was extracted from …
in adults. The current study aims to determine whether neurocognitive deficits also predict
ongoing or emergent suicidal behaviour in young people with affective disorders. Methods
Participants were aged 12-30 years and presented to early intervention youth mental health
clinics between 2008 and 2018. In addition to clinical assessment a standardised
neurocognitive assessment was conducted at baseline. Clinical data was extracted from …
Background
Neurocognitive impairment is recognised as a risk factor for suicidal behaviour in adults. The current study aims to determine whether neurocognitive deficits also predict ongoing or emergent suicidal behaviour in young people with affective disorders.
Methods
Participants were aged 12-30 years and presented to early intervention youth mental health clinics between 2008 and 2018. In addition to clinical assessment a standardised neurocognitive assessment was conducted at baseline. Clinical data was extracted from subsequent visits using a standardised proforma.
Results
Of the 635 participants who met inclusion criteria (mean age 19.6 years, 59% female, average follow up 476 days) 104 (16%) reported suicidal behaviour during care. In 5 of the 10 neurocognitive domains tested (cognitive flexibility, processing speed, working memory, verbal memory and visuospatial memory) those with suicidal behaviour during care were superior to clinical controls. Better general neurocognitive function remained a significant predictor (OR=1.94, 95% CI 1.29- 2.94) of suicidal behaviour in care after controlling for other risk factors.
Limitations
The neurocognitive battery used was designed for use with affective and psychotic disorders and may not have detected some deficits more specific to suicidal behaviour.
Conclusion
Contrary to expectations, better neurocognitive functioning predicts suicidal behaviour during care in young people with affective disorders. While other populations with suicidal behaviour, such as adults with affective disorders or young people with psychotic disorders, tend to experience neurocognitive deficits which may limit their capacity to engage in some interventions, this does not appear to be the case for young people with affective disorders.
Elsevier
以上显示的是最相近的搜索结果。 查看全部搜索结果