The role of autophagy in neurodegenerative disease
RA Nixon - Nature medicine, 2013 - nature.com
… regulating autophagy cause neurodegenerative diseases … disease, amyotrophic lateral
sclerosis and familial Parkinson's disease, defects arise at different stages of the autophagy …
sclerosis and familial Parkinson's disease, defects arise at different stages of the autophagy …
Compromised autophagy and neurodegenerative diseases
FM Menzies, A Fleming, DC Rubinsztein - Nature Reviews …, 2015 - nature.com
… , autophagy dysfunction has also been implicated in the pathogenesis of various diseases.
… of how perturbations in autophagy are linked with neurodegenerative diseases and the …
… of how perturbations in autophagy are linked with neurodegenerative diseases and the …
Autophagy gone awry in neurodegenerative diseases
E Wong, AM Cuervo - Nature neuroscience, 2010 - nature.com
… as the nature of the autophagic defect in different neurodegenerative disorders, are now …
autophagic dysfunction in neurodegeneration and the importance of identifying the autophagic …
autophagic dysfunction in neurodegeneration and the importance of identifying the autophagic …
Autophagy in neurodegenerative diseases: pathogenesis and therapy
F Guo, X Liu, H Cai, W Le - Brain pathology, 2018 - Wiley Online Library
… diseases and neurodegenerative diseases 17, 47, 78. Many studies have shown … autophagy
is closely linked with neurodegenerative diseases. For example, the amount of autophagic …
is closely linked with neurodegenerative diseases. For example, the amount of autophagic …
Control of autophagy as a therapy for neurodegenerative disease
H Harris, DC Rubinsztein - Nature reviews neurology, 2012 - nature.com
… Pharmacological induction of autophagy can enhance the clearance of intracytoplasmic …
animal models of neurodegenerative diseases. In this Review, the autophagic machinery and …
animal models of neurodegenerative diseases. In this Review, the autophagic machinery and …
Association between autophagy and neurodegenerative diseases
N Fujikake, M Shin, S Shimizu - Frontiers in neuroscience, 2018 - frontiersin.org
… Next, we review how autophagy is involved in the pathology of several neurodegenerative
diseases. We also summarize the therapeutic effects of autophagy-modulating compounds on …
diseases. We also summarize the therapeutic effects of autophagy-modulating compounds on …
The function of autophagy in neurodegenerative diseases
Y Kiriyama, H Nochi - International journal of molecular sciences, 2015 - mdpi.com
… with neurodegeneration in adulthood. In this review, we focus on the recent findings …
the autophagic process and the involvement of autophagy in neurodegenerative diseases. …
the autophagic process and the involvement of autophagy in neurodegenerative diseases. …
Targeting autophagy in neurodegenerative diseases
… Figure 1Autophagy impairment in neurodegenerative diseases. Possible defects that could
alter the regulation and induction of macroautophagy in various neurodegenerative disorders…
alter the regulation and induction of macroautophagy in various neurodegenerative disorders…
Autophagy in neurodegenerative disease: friend, foe or turncoat?
RA Nixon - Trends in neurosciences, 2006 - cell.com
… the nervous system is so vulnerable to diseases that impair lysosomal system function, and
… to neurodegenerative disease have functions in the endocytic and autophagic pathways [ …
… to neurodegenerative disease have functions in the endocytic and autophagic pathways [ …
Neuronal autophagy and neurodegenerative diseases
JH Son, JH Shim, KH Kim, JY Ha, JY Han - Experimental & molecular …, 2012 - nature.com
… Disease causing proteins affecting various types of autophagy in common neurodegenerative
diseases. Familial forms of the common neurodegenerative diseases, such as AD, PD, HD …
diseases. Familial forms of the common neurodegenerative diseases, such as AD, PD, HD …
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