[HTML][HTML] Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats

AB Aras, M Guven, T Akman, A Ozkan… - Neural regeneration …, 2015 - journals.lww.com
Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that
daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle
cerebral artery occlusion were intraperitoneally administered daidzein. Biochemical and
immunohistochemical tests showed that superoxide dismutase and nuclear respiratory
factor 1 expression levels in the brain tissue decreased after ischemia and they increased
obviously after daidzein administration; malondialdehyde level and apoptosis-related …
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