… potential of the aminopyrazoles, we prepared a series of new pyrazole derivatives and
evaluated their toxicological profile using Artemia salina, Daphnia magna and their cytotoxic …

… In the present paper, new pyrazoline derivatives were synthesized and investigated for
their antiproliferative effects on AsPC-1 human pancreatic adenocarcinoma, U87, and U251 …

… In this study, reaction of chalconated pyrazole derivative 1 with diethyl malonate under two
different reaction conditions was also investigated as shown in Scheme 2. Therefore, reaction …

… Furthermore, the pyrazole derivative celecoxib 2 and SC236 3, have been found to exhibit
potential antimigratory activity, inhibit neovascularization, decrease VEGF production and …

… structures of pyrazole and pyrazoline derivatives. … synthesis of new pyrazoline derivatives
from new chalcones and these synthesized compounds were screened potential anticancer …

… This study has demonstrated the apoptosis-inducing activity of new pyrazole derivatives,
which is in close correlation with their cytotoxicity in the HepG2 cancer cells. The most active …

… also reported the anticancer effects of celecoxib, a pyrazole derivative used as a … derivatives
[27-29], herein we report the synthesis and biological evaluation of a series of new pyrazole-…

… Our study was extended to prepare another new bipyridine derivatives including the pyrazole
moiety via multi-component reaction. Thus, the reaction of 3-acetylpyrazole derivative 1 …

… activity than most other pyrazoline derivatives synthesized in this study. Compounds b15
and b16 will be tested further to improve characterization of their antitumor activity. …

… derivatives 13a,b. Upon treatment 13a,b with a mixture of hydrochloric acid and acetic acid
gave pyrazole derivatives 14a,… 98% afforded pyrazole derivative 17a (Scheme 3).Citation 18 …