Nickel-catalyzed C–CN bond formation via decarbonylative cyanation of esters, amides, and intramolecular recombination fragment coupling of acyl cyanides

A Chatupheeraphat, HH Liao, SC Lee… - Organic letters, 2017 - ACS Publications
An efficient nickel-catalyzed decarbonylative cyanation reaction which allows the direct
functional-group interconversion of readily available esters into the corresponding nitriles
was developed. This reaction successfully offers access to structurally diverse nitriles with
high efficiency and excellent functional-group tolerance and provides a good alternative to
classical synthetic pathways from diazonium salts or organic halide compounds.

[引用][C] Nickel-Catalyzed C–CN Bond Formation via Decarbonylative Cyanation of Esters, Amides, and Intramolecular Recombination Fragment Coupling of Acyl …

C Adisak, L Hsuan-Hung, L Shao-Chi, R Magnus - 2017
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