Nitazoxanide in acute rotavirus diarrhea: a randomized control trial from a developing country

S Mahapatro, N Mahilary… - Journal of tropical …, 2017 - Wiley Online Library
Background. Acute diarrhea is one of the leading causes of childhood mortality, with
rotavirus being an important pathogen. Nitazoxanide, an antiparasitic agent, has been
shown to inhibit rotavirus. Objective. This double‐blind, randomized trial was designed to
study the role of nitazoxanide in acute rotavirus diarrhea. Methods. Of 174 children (12
months to 5 years) with acute diarrhea, 50 rotavirus positive cases were randomized. The
intervention group received syrup nitazoxanide twice daily (100 mg in 12–47 months, 200 …

Nitazoxanide in acute rotavirus diarrhea: a randomized control trial from a developing country.

SM Samarendra Mahapatro, NM Nijwm Mahilary… - 2017 - cabidigitallibrary.org
Background. Acute diarrhea is one of the leading causes of childhood mortality, with
rotavirus being an important pathogen. Nitazoxanide, an antiparasitic agent, has been
shown to inhibit rotavirus. Objective. This double-blind, randomized trial was designed to
study the role of nitazoxanide in acute rotavirus diarrhea. Methods. Of 174 children (12
months to 5 years) with acute diarrhea, 50 rotavirus positive cases were randomized. The
intervention group received syrup nitazoxanide twice daily (100 mg in 12-47 months, 200 …
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