… Notch signaling in cDC differentiation in vivo, we hypothesized that it would facilitate cDC
differentiation in vitro… properties and superior T cell cross-priming capacity in vivo. Furthermore, …

… Notch signaling in cDC differentiation in vivo, I hypothesized that it would facilitate cDC
differentiation in vitro… Cross-presenting classical dendritic cells in cancer and immunotherapy…….…

… Dendritic cells (DCs) play critical roles in regulating the innate … found that Notch signaling
facilitated generation of CD141 + … effect of DL1-Notch signaling on in vitro human iPSC-derived …

… functional cross-presenting activity. … macrophages and dendritic cells, in the context of Notch
signal modulation. … in vitro generation and T cell cross-priming (74). Moreover, conventional …

… Notch function in T cells promotes inflammation-associated cancer development. Surprisingly,
we found that loss of Notch signaling in T cells … indicate that ex vivo Notch-primed DCs …

Two studies show that adding NOTCH … , these NOTCH-DCs more closely resemble in vivo
DCs transcriptionally and functionally. This will be extremely valuable for studying DCs in vitro …

… types of human dendritic cells (DCs) in vitro is critical for … Notch signaling and GM-CSF for
promoting cDC1 generation… Our culture system will greatly facilitate the simultaneous and …

… CD8 + T cells and facilitates tumor-specific T cell responses. … marrow impaired the generation
of cDC1-like cells in vitro and … The phenotype could not be rescued by Notch signaling, …

… classical dendritic cells is specialized for priming CD8 T cell … T cell help to DCs is necessary
for the generation of a CD8 T … be a functional cross-presenting DC subset in vivo 33 and at …

… , XCL1, promotes interaction between cross-presenting DC … DC activity have the potential
to synergize with both classical … + cross-presenting DCs are far more effective at generating …