[PDF][PDF] Notoginsenoside Ft1 promotes fibroblast proliferation via PI3K/Akt/mTOR signaling pathway
E Zhang, B Gao, L Yang, X Wu, Z Wang - researchgate.net
Wound healing requires the essential participation of fibroblasts, which is impaired in
diabetic foot ulcers (DFU). Notoginsenoside Ft1 (Ft1), a saponin from Panax notoginseng,
can enhance platelet aggregation by activating signaling network mediated through P2Y12,
and induce proliferation, migration, and tube formation in cultured human umbilical vein
endothelial cells. However, whether it can accelerate fibroblast proliferation and benefit
wound healing, especially DFU, has not been elucidated. In the present study, on human …
diabetic foot ulcers (DFU). Notoginsenoside Ft1 (Ft1), a saponin from Panax notoginseng,
can enhance platelet aggregation by activating signaling network mediated through P2Y12,
and induce proliferation, migration, and tube formation in cultured human umbilical vein
endothelial cells. However, whether it can accelerate fibroblast proliferation and benefit
wound healing, especially DFU, has not been elucidated. In the present study, on human …
Notoginsenoside Ft1 promotes fibroblast proliferation via PI3K/Akt/mTOR signaling pathway and benefits wound healing in genetically diabetic mice
E Zhang, B Gao, L Yang, X Wu, Z Wang - Journal of pharmacology and …, 2016 - ASPET
Wound healing requires the essential participation of fibroblasts, which is impaired in
diabetic foot ulcers (DFU). Notoginsenoside Ft1 (Ft1), a saponin from Panax notoginseng,
can enhance platelet aggregation by activating signaling network mediated through P2Y12
and induce proliferation, migration, and tube formation in cultured human umbilical vein
endothelial cells. However, whether it can accelerate fibroblast proliferation and benefit
wound healing, especially DFU, has not been elucidated. In the present study on human …
diabetic foot ulcers (DFU). Notoginsenoside Ft1 (Ft1), a saponin from Panax notoginseng,
can enhance platelet aggregation by activating signaling network mediated through P2Y12
and induce proliferation, migration, and tube formation in cultured human umbilical vein
endothelial cells. However, whether it can accelerate fibroblast proliferation and benefit
wound healing, especially DFU, has not been elucidated. In the present study on human …
