Novel diterpenoid acetylcholinesterase inhibitors from Salvia miltiorhiza

Y Ren, PJ Houghton, RC Hider, MJR Howes - Planta medica, 2004 - thieme-connect.com
Abstract Acetylcholinesterase (AChE, EC 3.1. 1.7) inhibitors are the only registered drugs
used to treat Alzheimer's disease (AD). New AChE inhibitors may contribute to the design of
new pharmaceuticals and supply information which will facilitate the understanding of the
interaction between inhibitors and the enzyme. The dried root of Salvia miltiorhiza is called
'Danshen'in China, and has been used for the treatment of cerebrovascular disease and
CNS deterioration in old age for over one thousand years. In this work, a modified Ellman …

Novel diterpenoid acetylcholinesterase inhibitors from Salvia miltiorhiza.

RYH Ren YuHao, PJ Houghton, RC Hider, MJR Howes - 2004 - cabidigitallibrary.org
Abstract Acetylcholinesterase (AChE, EC 3.1. 1.7) inhibitors are the only registered drugs
used to treat Alzheimer's disease (AD). New AChE inhibitors may contribute to the design of
new pharmaceuticals and supply information which will facilitate the understanding of the
interaction between inhibitors and the enzyme. The dried root of S. miltiorrhiza is
called'Danshen'in China, and has been used for the treatment of cerebrovascular disease
and CNS deterioration in old age for over one thousand years. In this work, a modified …
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