A simple relation of chemical processes for three-dimensional flow of a cross magnetofluid over bidirectional stretched surface is constructed. The impact of convective heat transport in the manifestation of non-linear thermal radiation and features of heat source–sink are also considered for heat transfer mechanism. Furthermore, in this research paper, the innovative relation between heterogeneous and homogeneous responses with equivalent diffusivities for reactant and autocatalysis is exploited. Apposite alterations are guaranteed to obtain ordinary differential equations (ODEs) with high nonlinearity. Numerically, the bvp4c technique is exploited to the interpret the structure of ODEs. Portrayals of temperature and concentration for cross liquid equivalent to abundant somatic parameters are presented graphically as well as in tabular form. Our results reveal that the temperature of the cross fluid decreases with fluctuation in the heat sink parameter. Furthermore, it is perceived from the figures that the concentration of the cross fluid reduces for higher values of chemical reaction parameters.