Metabolic syndrome (MS), the commonly used term for the clustering of obesity, insulin
resistance, hypertension, and dyslipidemia, affects millions of people worldwide, and is
associated with an increased risk of cardiovascular disease and type 2 diabetes. Recently, it
has been suggested that obstructive sleep apnea (OSA), an increasingly prevalent
condition, may contribute to the development of MS and diabetes. Despite substantial
evidence from both clinical and population studies to suggest an independent link between …

Metabolic syndrome (MS) is a heterogeneous condition associated with increased
cardiovascular risk. There is growing evidence from experimental, translational, and clinical
investigations that has suggested that obstructive sleep apnea (OSA) is associated with
prevalent and incident components of MS and MS itself. The biological plausibility is
supportive, primarily related to one of the main features of OSA, namely intermittent hypoxia:
increased sympathetic activation with hemodynamic repercussions, increased hepatic …