Bronchodilating drugs for chronic obstructive pulmonary disease: current status and future trends

P Montuschi, G Ciabattoni - Journal of medicinal chemistry, 2015 - ACS Publications
Inhaled dual-pharmacology compounds, combining … or synergistic bronchodilation over
either inhaled antimuscarinic … in COPD patients with low risk for exacerbations, more symptoms, …

Aerosol delivery devices for obstructive lung diseases

RA Pleasants, DR Hess - Respiratory Care, 2018 - rc.rcjournal.com
… The face mask seal can impact facial and eye deposition of … of inhaled bronchodilators. Their
cost is greater than that of jet … driven nebulization produced a significant decrease in the risk

Double-edged sword?: long-acting bronchodilators in chronic obstructive pulmonary disease

PG Woodruff - JAMA Internal Medicine, 2013 - jamanetwork.com
… Some data suggest that the combination of an LABA and an inhaled corticosteroid (ICS)
attenuates the risk of overall mortality in asthma, but this point has not been proven. Meta-…

[HTML][HTML] The use of rhDNAse in severely ill, non-intubated adult asthmatics refractory to bronchodilators: a pilot study

RA Silverman, F Foley, R Dalipi, M Kline, M Lesser - Respiratory medicine, 2012 - Elsevier
… opinion of the investigator increase the risk of adverse effects with treatment. … nebulized
albuterol and 0.5 mg nebulized ipratropium given. After completion of this second bronchodilator

Safety and tolerability of inhaled budesonide in children in the Steroid Treatment As Regular Therapy in early asthma (START) trial

M Silverman, AL Sheffer, PV Díaz… - Pediatric Allergy and …, 2006 - Wiley Online Library
… of increased risk of systemic or ocular adverse events with … In conclusion, the addition of
once-daily inhaled budesonide … pre- and post-bronchodilator values for forced expiratory volume …

Preservatives in eyedrops: the good, the bad and the ugly

C Baudouin, A Labbé, H Liang, A Pauly… - … in retinal and eye …, 2010 - Elsevier
… The Pharmacopoeia recommends that eye drops must contain an antimicrobial agent (… a
risk of potentially severe eye infection as well as the alteration of the formulation. Eye drops are …

Clinical efficacy and safety of the combination of ipratropium bromide and fenoterol inhaled via the Respimat© Soft Mist™ inhaler for relief of airflow obstruction

W Vincken - Expert Review of Respiratory Medicine, 2008 - Taylor & Francis
… of increased risk of side effects on the one hand and loss of efficacy on the other Citation[9].
The anticholinergic (AC) agents in clinical use as inhaled bronchodilators are synthetic …

Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled …

S Singh, YK Loke, PL Enright, CD Furberg - Bmj, 2011 - bmj.com
… trials on the risk of mortality associated with inhaled tiotropium … the long term trials, using
Visual Rx version 2.0.The number … morbidity and the use of inhaled bronchodilators. Int J Chron …

Risk for death associated with medications for recently diagnosed chronic obstructive pulmonary disease

TA Lee, AS Pickard, DH Au, B Bartle… - Annals of internal …, 2008 - acpjournals.org
… , which is similar to the 0.80 reduction in risk that we observed for inhaled corticosteroids
and the 0.78 reduction for the combination of inhaled corticosteroids and long-acting β-agonists …

New treatment option for chronic obstructive pulmonary disease: two long-acting bronchodilators in a single metered-dose inhaler

TH Self, S Ellingson - The American Journal of Medicine, 2017 - Elsevier
… Combination long-acting inhaled bronchodilators are central to the management of patients
… ICS therapy in COPD patients is associated with increased risk of pneumonia.4, 5 Therefore, …