Open and distance learning is now seen as a legit-imate means through which an effective science and technology education can be disseminated. There are many factors which support this argument. With the advancements of information and communication technologies (ICT), have given rise to new opportunities for sharing information, resources, and experiences, as well as providing networking opportunities with student peers, tutors, and the institution. All these factors suggest that ODL may be the solution for overcoming the gap between those who have had access to science and technology (S&T) education and those who have not. It is now proven fact that scientific knowledge is a pre-requisite to solve each country’s pressing social and economic problem, to transform their societies and to have positive impact on the standards of living and quality of life of the poorest of poor any society. In present situation S&T capacity building is an indispensable tool for promoting sustainable and inclusive globalization. In the proposed paper, an experience from IGNOU in delivering science programme through ODL mode is shared.